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Peptex Laboratories GHXXX -MK677 SAMPLE PACK - 20mg x 20 capsules - 99.4% Purity - Best Quality Guaranteed MK-677

Peptex Laboratories GHXXX -MK677 SAMPLE PACK - 20mg x 20 capsules - 99.4% Purity - Best Quality Guaranteed MK-677
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Peptex Laboratories GHXXX -MK677 SAMPLE PACK - 20mg x 20 capsules - 99.4% Purity - Best Quality Guaranteed MK-677
  • Stock: In Stock
  • Model: MK677SMPL
158 samples sold
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£15.00
Ex Tax: £15.00

We are often contacted for samples or freebies - usually NOT be professional researchers or establishments, but more so private individuals conducting their own private research.

We will be adding to our offering of sample SARM & more packages - our MK677 is the first of many to come, but this listing is for a 20 capsule pouch, for those who may doubt our quality - to buy at a lower cost, to test and verify. Let there be no doubt of the quality of products we supply.


UPDATED OVERVIEW OF THIS AMAZING GH SECRETAGOGUE.


Peptex Laboratories MK-677 – GHXXX – an overview.

MK-677 (also known as ibutamoren), promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). 

It is often regarded to as a SARM when this is not correct – it is a GH Secretagogue.

Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors (GHSR) in the brain. 

Activated GHSR stimulates growth hormone release from the brain. Clinical studies describe only the effects ibutamoren has on appetite and as expected, like ghrelin, ibutamoren increases it. So, If utilising in-vivo bear this very clear effect in mind.

GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition.

Therefore, we can expect that ibutamoren may also affect these functions. It increases growth hormone levels with little or no increase in other hormones, such as cortisol. Cortisol suppresses the immune system, reduces wound healing, and impairs learning and memory, and it’s usually not good to have this hormone elevated.

BENEFITS OF MK-677

The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies. Read on for a more in-depth look at these benefits. 

Helps Build Musculature – possible aid in muscle wastage disease variants? 

Ibutamoren is frequently used as an anabolic substance, to increase lean body mass. It is now sold on many grey area websites selling other – potentially ‘harder’ supplements. It is growing rapidly within the bodybuilding, CrossFit, and athletic communities – despite its WADA status.

It is orally active and can be taken once a day. MK-677 stimulates Growth Hormone and IGF-1 which factors in significantly to maintaining lean body mass. Growth Hormone is believed by many to stimulate an increase in muscle size and strength and the ability of MK-677 to increase Growth Hormone production make it a popular choice.

As an example - one study of 24 obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR)

Reduces Muscle Wasting

MK-677 has shown in recent studies (note while I am citating here all info is detailed on PubMed) to alleviate muscle wasting that can be caused by a decline in protein within an individual’s diet. In one study a group of healthy young adults were tested to determine if MK-677 could reverse protein catabolism and the results proved to be quite positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.

Increases Bone Density

Several studies have indicated that long-term use of MK-677 can have tremendous results to increase bone mineral density. This finding can benefit several populations including obese individuals, older adults, and women with menopause. 

These distinct populations can have detrimental health problems due to low bone mineral density and MK-677 has proven to be an effective treatment for many of them.

In 24 healthy obese male volunteers, ibutamoren increased bone turnover.

In 187 elderly adults (65 years or older), ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies.

In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.

The groups of people who serve to benefit by MK-677’s ability to increase bone density must research the possibility of any long-term side effects since increases in bone density typically take more than a year’s use. 

Improves Sleep

Since Growth Hormone is known to help improve sleep quality, it is commonly thought that Ibutamoren Mesylate can assist with sleep quality since it stimulates production in Growth Hormone.

A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration.

Apart from scientific studies, there have been many reports of subjective improvements in sleep quality (anecdotally) across many internet forums.

Combats Aging and May Increase Longevity

As seen with other hormones in the body, Growth Hormone naturally begins a steady decline once a certain age is hit. Individuals who are aging can benefit from taking MK 677 since Growth Hormone and IGF-1 will be increased in the body among its consumption. Aging individuals who take MK 677 can improve their overall hormone profiles as they give their declining GH levels (Growth Hormone levels) a boost. This has a great beneficial effect on the body, and I am told reportedly – some GP Clinicians are now prescribing MK-677 in lieu of HGH and other GHRH/GHRP peptide analogues designed to increase GH levels.

In a study with 65 elderly men and women, daily ibutamoren increased GH and IGF-1 levels to those of healthy young adults without serious adverse effects.

In another study with 24 obese males, ibutamoren rejuvenated the growth hormone profile.

May Have Nootropic Effects

Since MK-677 shares a lot of similar qualities to Ghrelin and binds to its receptors, it is believed that MK 677 can have the same effects on the brain that Ghrelin has.

However, there are no studies that confirm whether MK 677 has direct nootropic effects on the brain. Scientists do have hope though that a couple of noticeable indirect methods may explain how MK 677 can be of assistance to cognitive function. Looking back at the previous section, one method that shows promise is Ibutamoren’s ability to improve sleep quality by increasing REM sleep. Obtaining the proper amount of sleep each night is extremely important when trying to achieve adequate cognitive function. MK-677 can improve cognitive function by assisting individuals with the ability to get a good night’s rest. 

The ability of MK-677 to stimulate IGF-1 production can also indirectly improve cognitive function based on IGF-1’s role in cognitive function. One study indicated that IGF-1 positively affected participants’ ability to perform well on cognitive tests. We know that sleep is essential for good cognitive function.

Beneficial in Treating Growth Hormone Deficiency

Ibutamoren can increase growth hormone, IGF-1, and IGFBP-3 levels in children with growth hormone deficiency. Furthermore, these effects are achieved without changing the concentrations of prolactin, glucose, triiodothyronine (T3), thyroxine (T4), thyrotropin, cortisol, or insulin.

In severely GH-deficient men, ibutamoren increased IGF-1 and growth hormone, with no significant changes in cortisol, PRL, and thyroid hormone levels. However, insulin and glucose were increased.

SIDE EFFECTS OF MK-677

MK 677 has not produced very many noticeable side effects for its users to be concerned about, but certain populations may have some side effects to look out for.

Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK-677. Symptoms associated with these conditions could possibly be exacerbated using MK 677. As with any other compound, correct dosing, and usage of MK-677 is the key. In studies that looked at how MK-677 increases muscle mass, the dosage was the vital key. Side effects of MK-677 are usually the result of a handful of two things: improper dosage and extended use/abuse.

Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which can/may potentially include:

  • Increased appetite
  • Lethargy
  • Joint pain if you have previous medical conditions or elevated hormone levels
  • Insulin resistance
  • Possible increase in prolactin levels, which can be controlled (the reason having regular blood tests is important)

When dosed properly, the side effects of MK-677 are minimal to none – this is reflected in hundreds of studies to date. Abuse, like anything, can cause issues so it is vital the compound is respected and used as intended or directed. The results from using MK-677 are evident in just a couple of days and with proper correct dosing.

Research references/citations can be provided upon request. It is important to note the information provided is for the use of Peptex Laboratories MK677 GHXXX in the use of in-vitro and/or in-vivo laboratory research use only. Any statements outside this, while Dr Wade Ackley is qualified to provide such advice, as it is more generic in nature it is intended for informational, entertainment and educational purposes only.

Disclaimer: We do not make any claims about the products sold on this website. No information provided on this website has been evaluated by the FDA or MHRA. Any information provided on this website is provided to the best of our knowledge and is not intended to replace the advice of a qualified medical practitioner. Any testimonials or product reviews provided by our customers are not the views of Peptex-labs.com and should not be taken as recommendation or fact. All products are strictly for research use only and category names and in relation to in-vitro testing and research and not human use.

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